UNESCO has been globally given the responsibility for coordinating the education sector response to HIV/AIDS. Responding to the given responsibilities, UNESCO Bangkok in collaboration with UNAIDS developed an advocacy kit “HIV/AIDS and Education: A Toolkit for Ministries of Education” targeted to the senior and mid-level officials of MOE. The major objective of this guide was to encourage and help particularly education Ministry/Department officials across the South East Asia and Pacific region, to reinforce their commitment, increase awareness of the impact of HIV/AIDS, and collaborate to take actions against the disease. This toolkit was translated and adapted in different languages in different countries and UNESCO Dhaka has undertaken the initiative and gave the responsibility to Bangladesh AIDS Prevention Society (BAPS) for translation and adaptation of this toolkit, which was finalized through a three-day national workshop. This toolkit has been used as an effective tool for HIV/AIDS advocacy and awareness raising.